Gokuldham Society is a residential Society of Mumbai in which six Indian families, respectively headed by Jethalal Champaklal Gada, Taarak Mehta, Aatmaram Tukaram Bhide, Dr. Hansraj Hathi, Sardar Roshan Singh Harjeet Singh Sodhi and Krishnan Subramaniam Iyer live. There are also other individual characters like Patrakar poptalal Pandey, Sundarlal, Abdul, Pinku, Natwarlal Prabhashankar Udhaiwala, Bagheshwar Dadukh Udhaiwala and others.
The members of these families have keen psychological attachment of love and sympathy for one another that makes them the members of a suppositious greater family. In the episodes of the show, the families are shown to live a life that a typical Indian family lives, but the characters, more often than not Jethalal, get into petty troubles cropping up from daily life activities that intensify in a comical manner, giving rise to laughter among the viewers. Humour in the show is further heightened by the individual quirks of the characters.